OXYCONTIN may perhaps bring about severe hypotension, including orthostatic hypotension and syncope in ambulatory clients. You can find a heightened hazard in clients whose ability to take care of blood pressure has presently been compromised by a lessened blood volume or concurrent administration of certain CNS depressant medications (e.
OxyContin is created in a way which makes it challenging to be misused by drug seekers. The tablet is challenging to crush or break and sorts a thick, sticky gel if combined with drinking water which implies it can not be injected.
Frequent communication is essential among the prescriber, other associates from the Health care crew, the client, as well as the caregiver/family for the duration of periods of adjusting analgesic necessities, such as Original titration. Through use of opioid therapy for an extended length of time, periodically reassess the ongoing have to have for the use of opioid analgesics.
How long opioid withdrawal lasts relies on the opioid you have been getting and whether it's a brief-acting or prolonged performing opioid.
Drug habit can be a cluster of behavioral, cognitive, and physiological phenomena that will include things like a powerful desire to go ahead and take drug, complications in controlling drug use (e.
When OXYCONTIN get more info therapy is initiated, discontinue all other opioid analgesics other than Individuals applied on an as required basis for breakthrough discomfort when ideal.
Usually do not use for the duration of pregnancy and breastfeeding Until specifically encouraged by your health practitioner. Maintain this medicine in a secure area and out on the achieve of youngsters and pets. Accidental ingestion check here of even 1 dose of OxyContin, especially by young children, could be deadly.
Using OXYCONTIN in patients with acute or significant bronchial asthma in an unmonitored location or in the absence of resuscitative tools is contraindicated.
Circumstances of adrenal insufficiency are already documented with opioid use, a lot more often following larger than just one thirty day period of use.
The background danger of key start defects and miscarriage to the indicated inhabitants is unfamiliar. All pregnancies have a background possibility of start defect, decline, or other adverse results.
Teach individuals and caregivers on how to recognize respiratory melancholy and emphasize the significance of contacting 911 or having emergency professional medical help right away in the more info celebration of a recognized or suspected overdose.
Concomitant utilization of OXYCONTIN with CYP3A4 inducers or discontinuation of a CYP3A4 inhibitor could lessen oxycodone plasma concentrations, lessen opioid efficacy or, perhaps, lead to a withdrawal syndrome inside of a affected person who experienced designed Bodily dependence to oxycodone.
Talk about Together with the affected person and caregiver the availability of naloxone for that emergency procedure of opioid overdose, both equally when initiating and renewing remedy with OXYCONTIN. Inform clients and caregivers about the assorted means to obtain naloxone as permitted by person condition naloxone dispensing and prescribing needs or guidelines (e.
Read the Medication Guideline furnished by your pharmacist Before you begin having extended-release oxycodone and every time you obtain a refill. When you've got any queries, request your physician or pharmacist.